
Andreas Heuer
Research team manager

Publications
Displaying of publications. Sorted by year, then title.
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
Jana Rájová, Marcus Davidsson, Martino Avallone, Morgan Hartnor, Patrick Aldrin-Kirk, et al.
(2023) Molecular Therapy - Methods and Clinical Development, 29 p.381-394
Journal articleA comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates
Danish M. Anwer, Francesco Gubinelli, Yunus A. Kurt, Livija Sarauskyte, Febe Jacobs, et al.
(2023) PLoS ONE, 18
Journal articleAstrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
Isaac Canals, Andrea Comella-Bolla, Efrain Cepeda-Prado, Natalia Avaliani, James A Crowe, et al.
(2023) Brain Communications, 5 p.1-16
Journal articleAutomated quantification of neuronal swellings in a preclinical rodent model of Parkinson's disease detects region-specific changes in pathology
Luis Quintino, Francesco Gubinelli, Livija Sarauskyte, Elin Arvidsson, Marcus Davidsson, et al.
(2022) Journal of Neuroscience Methods, 378
Journal articleLateralized deficits after unilateral AAV-vector based overexpression of alpha-synuclein in the midbrain of rats on drug-free behavioral tests
F. Gubinelli, G. Cazzolla, M. Negrini, I. Kulacz, A. Mehrdadian, et al.
(2022) Behavioural Brain Research, 429
Journal articleA novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
Patrick Aldrin-Kirk, Malin Åkerblom, Tiago Cardoso, Sara Nolbrant, Andrew F. Adler, et al.
(2022) Stem Cell Reports, 17 p.159-172
Journal articleSmall scale adeno-associated virus-vector production for preclinical gene delivery based on chloroform precipitation
Marcus Davidsson, Andreas Heuer
(2022) Neural Regeneration Research, 17 p.99-100
Journal article reviewSequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits
Matilde Negrini, Giuseppe Tomasello, Marcus Davidsson, Alexis Fenyi, Cécile Adant, et al.
(2022) Journal of Parkinson's Disease, 12 p.1133-1153
Journal articleEditorial : Regeneration and Brain Repair
Daniella Rylander Ottosson, Sofia Grade, Andreas Heuer
(2021) Frontiers in Cellular Neuroscience, 15
Journal article (comment)Neurotransmitter Release of Reprogrammed Cells Using Electrochemical Detection Methods
Andreas Heuer
(2021) Methods in Molecular Biology, 2352 p.201-226
Book chapterDopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model
Sophie V. Precious, Gaynor A. Smith, Andreas Heuer, Ines Jaeger, Emma L. Lane, et al.
(2020) Frontiers in Neuroscience, 14
Journal articleA comparison of AAV-vector production methods for gene therapy and preclinical assessment
Marcus Davidsson, Matilde Negrini, Swantje Hauser, Alexander Svanbergsson, Marcus Lockowandt, et al.
(2020) Scientific Reports, 10
Journal articleAAV Production Everywhere : A Simple, Fast, and Reliable Protocol for In-house AAV Vector Production Based on Chloroform Extraction
Matilde Negrini, Gang Wang, Andreas Heuer, Tomas Björklund, Marcus Davidsson
(2020) Current Protocols in Neuroscience, 93 p.103-103
Journal articleSingle cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K. Björklund, Yogita Sharma, et al.
(2020) Nature Communications, 11
Journal articleCellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Margarita Chumarina, Kaspar Russ, Carla Azevedo, Andreas Heuer, Maria Pihl, et al.
(2019) Acta Neuropathologica Communications, 7
Journal articleSeeding of protein aggregation causes cognitive impairment in rat model of cortical synucleinopathy
Elena Espa, Erik K.H. Clemensson, Kelvin C. Luk, Andreas Heuer, Tomas Björklund, et al.
(2019) Movement Disorders, 34 p.1699-1710
Journal articleMolecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing
Marcus Davidsson, Paula Díaz-Fernández, Marcos Torroba, Oliver D. Schwich, Patrick Aldrin-Kirk, et al.
(2018) RNA, 24 p.673-687
Journal articleChemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
Patrick Aldrin-Kirk, Andreas Heuer, Daniella Ottosson, Marcus Davidsson, Bengt Mattsson, et al.
(2018) Neurobiology of Disease, 109 p.148-162
Journal articleIn vivo electrochemical studies of optogenetic control of glutamate signaling measured using enzyme-based ceramic microelectrode arrays
Jason J. Burmeister, Francois Pomerleau, Jorge E. Quintero, Peter Huettl, Yi Ai, et al.
(2018) Neuromethods, 130 p.327-351
Book chapterAutomated Operant Assessments of Huntington's Disease Mouse Models
Emma Yhnell, Andreas Heuer
(2018) Methods in molecular biology (Clifton, N.J.), 1780 p.143-162
Journal articleDirectly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
Natalia Avaliani, Ulrich Pfisterer, Andreas Heuer, Malin Parmar, Merab Kokaia, et al.
(2017) Stem Cells International, 2017
Journal articleGeneration of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
Sara Nolbrant, Andreas Heuer, Malin Parmar, Agnete Kirkeby
(2017) Nature Protocols, 12 p.1962-1979
Journal articlePredictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease
Agnete Kirkeby, Sara Nolbrant, Katarina Tiklova, Andreas Heuer, Nigel Kee, et al.
(2017) Cell Stem Cell, 20 p.135-148
Journal articleIAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells
Daniela Lehnen, Serena Barral, Tiago Cardoso, Shane Grealish, Andreas Heuer, et al.
(2017) Stem Cell Reports, 9 p.1207-1220
Journal articleHESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
Andreas Heuer, Agnete Kirkeby, Ulrich Pfisterer, Marie E. Jönsson, Malin Parmar
(2016) Experimental Neurology, 282 p.78-85
Journal articleDREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
Patrick Aldrin-Kirk, Andreas Heuer, Gang Wang, Bengt Mattsson, Martin Lundblad, et al.
(2016) Neuron, 90 p.955-968
Journal articleMonosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
Shane Grealish, Andreas Heuer, Tiago Cardoso, Agnete Kirkeby, Marie Jönsson, et al.
(2015) Stem Cell Reports, 4 p.975-983
Journal articleHuman ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
Shane Grealish, Elsa Diguet, Agnete Kirkeby, Bengt Mattsson, Andreas Heuer, et al.
(2014) Cell Stem Cell, 15 p.653-665
Journal article