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Skeletal muscle atrophy in r6/2 mice - altered circulating skeletal muscle markers and gene expression profile changes.

  • Anna Magnusson-Lind
  • Marcus Davidsson
  • Edina Silajdzic
  • Christian Hansen
  • Andy McCourt
  • Sarah J Tabrizi
  • Maria Björkqvist
Publishing year: 2014
Language: English
Pages: 13-24
Publication/Series: Journal of Huntington's disease
Volume: 3
Issue: 1
Document type: Journal article
Publisher: IOS Press

Abstract english

In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology, including progressive skeletal muscle wasting, and common skeletal muscle gene expression changes have been shown in HD mice and human HD.


  • Neurology


  • Biomarkers in Brain Disease
  • Molecular Neurobiology
  • Neural Plasticity and Repair
  • ISSN: 1879-6397
Marcus Davidsson
E-mail: marcus [dot] davidsson [at] med [dot] lu [dot] se

Molecular Neuromodulation unit
Wallenberg Neuroscience Center
Department of Experimental Medical Science
BMC A10, 221 84 Lund, Sweden
Phone: +46 46 222 68 36
e-Mail: tomas [dot] bjorklund [at] med [dot] lu [dot] se