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In vivo massively parallel functional genetic screening

Advancements in viral vector technology, molecular biology tools and massively-parallel sequencing strategy has opened up for an entirely new view on in vivo studies of gene function and molecular mechanisms. In this project we aim to develop a novel toolset where a priory hypothesis based, iterative dissection of function in vitro and in vivo is replaced by an unbiased massively-parallel in vivo screening approach.