Patrick Aldrin-Kirk | MSc, PhD
PhD student in MNM until 2018
PhD thesis
On April 13, 2018 Patrick Aldrin-Kirk of the MNM team with great success defended his PhD thesis.
Titled "Dissection of basal ganglia circuitry and DA grafts in Parkinson’s disease using viral vectors" this thesis very nicely summarises the efforts in the MNM team to elucidate mechanisms behind multiple forms of dyskinesias in Parkinson's disease and furthers the field of chemogenetics. Thesis opponent was Vania Broccoli, San Raffaele Scientific Institute Milan, Italy. Congratulations Patrick!
Publications
Aldrin-Kirk P, Björklund T.
Methods Mol Biol. 2019;1937:59-87. doi: 10.1007/978-1-4939-9065-8_4.
- PMID: 30706390
Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, Dridi L, Martins C, Levade T, Stacey KB, Davis DM, Dyer A, Clément N, Björklund T, Ali RR, Agbandje-McKenna M, Rahim AA, Pshezhetsky A, Waddington SN, Linden RM, Bigger BW, Henckaerts E.
Brain. 2018 Jul 1;141(7):2014-2031. doi: 10.1093/brain/awy126.
- PMID: 29788236
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing.
Davidsson M, Díaz-Fernández P, Torroba M, Schwich OD, Aldrin-Kirk P, Quintino L, Heuer A, Wang G, Lundberg C, Björklund T.
RNA. 2018 May;24(5):673-687. doi: 10.1261/rna.063925.117. Epub 2018 Jan 31.
- PMID: 29386333
Aldrin-Kirk P, Heuer A, Rylander Ottosson D, Davidsson M, Mattsson B, Björklund T.
Neurobiol Dis. 2018 Jan;109(Pt A):148-162. doi: 10.1016/j.nbd.2017.10.010. Epub 2017 Oct 14.
- PMID: 29037828
Aldrin-Kirk P, Heuer A, Wang G, Mattsson B, Lundblad M, Parmar M, Björklund T.
Neuron. 2016 Jun 1;90(5):955-68. doi: 10.1016/j.neuron.2016.04.017. Epub 2016 May 5.
- PMID: 27161524
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
Holmqvist S, Chutna O, Bousset L, Aldrin-Kirk P, Li W, Björklund T, Wang ZY, Roybon L, Melki R, Li JY.
Acta Neuropathol. 2014 Dec;128(6):805-20. doi: 10.1007/s00401-014-1343-6. Epub 2014 Oct 9.
- PMID: 25296989
Aldrin-Kirk P, Davidsson M, Holmqvist S, Li JY, Björklund T.
PLoS One. 2014 Jul 7;9(7):e100869. doi: 10.1371/journal.pone.0100869. eCollection 2014.
- PMID: 24999658